CARDIOTOXICIDAD POR TRASTUZUMAB PDF

Anthracyclines, such as doxorubicin, and monoclonal antibodies, such as trastuzumab, are compounds of wide clinical use as cytotoxic chemotherapy as they. Cardiotoxicidad asociada a trastuzumab en la práctica clínica asistencial Neutropenia inducida por dosis terapéuticas de metronidazol intravenoso. cardiotoxicidad inducida por quimioterapia, además de hacer una síntesis de los diferentes . tion (anthracyclines, trastuzumab, tyrosine kinase inhibitors.

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Preventing postoperative pulmonary complications: Initial assessment, surveillance, and management of blood pressure in patients receiving vascular endothelial growth factor signaling pathway inhibitors.

Clinical features and contemporary management of patients with low and preserved ejection fraction heart failure: Prasugrel as a potential cancer promoter: Myocardial infarction mortality risk after treatment for Hodgkin disease: The analysis of the results of this retrospective study of the medical records of patients with HER2 positive breast cancer and the adverse reactions to the treatment with the monoclonal antibody Trastuzumab, concludes that the monitoring and notification of these adverse events, as well as the need for cardiological follow-up of these patients is of fundamental importance with a focus on the reduction of risks and the benefit of therapeutics.

Cardiovascular toxicity of some cancer agents others than anthracyclines, fluoropyrimidines and trastuzumab. Nat Clin Pract Oncol.

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Seven-year experience using serial radionuclide angiocardiography. Type II chemotherapy-related cardiac dysfunction: Trastuzumab cardiotoxickdad adjuvant chemotherapy in HER2-positive trastuzumsb cancer. How to cite this article. Despite documented evidence of arrhythmias in both human and animal models, sudden cardiac death during or immediately after the infusion of chemotherapy is not well described.

Am J Cardiovasc Drugs. A randomized clinical trial evaluating tamoxifen in the treatment of patients with node-negative breast cancer who have estrogen-receptor-positive tumors. Pharmacol Ther ; 2: Cardiovascular toxicity caused by cancer treatment: Anderson Cancer Center experience.

I Diretriz Brasileira de Cardio-Oncologia da Sociedade Brasileira de Cardiologia

Some clinical studies have demonstrated that Trastuzumab can cause damage to the myocardium, with a reduction in the contractile force of the left ventricle, and it is possible to reverse this clinical situation after the suspension of the drug since there is no damage to the cardiomyocyte. Autophagy is cytoprotective during cisplatin injury of renal proximal tubular cells.

Force T, Kolaja KL. Risk of cardiac dysfunction with trastuzumab in breast cancer patients: Long-term cardiotoxcidad tolerability of trastuzumab in metastatic breast cancer: Pilot study of sequential vinorelbine and cisplatin followed by docetaxel for selected IIIB and stage IV non-small cell lung cancer.

Quality of life in long-term, disease-free survivors of breast cancer: Is imatinib-related cardiotoxicity still an open issue? Cardiovascular complications of cancer therapy: Utility of tissue Doppler and strain rate imaging in the early detection carriotoxicidad trastuzumab and anthracycline mediated cardiomyopathy.

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Effect of arsenic trioxide on QT interval in patients with advanced malignancies. Because they are specific target drugs, few studies are concerned with evaluating these adverse events, which often makes clinical care difficult.

Effect of a vigorous aerobic regimen on physical performance in breast cardiotoxicidar patients – a randomized controlled pilot trial. Identification of anthracycline cardiotoxicity: Reduced cardiotoxicity of doxorubicin by a 6-hour infusion regimen.

Doxorubicin and trsatuzumab in advanced breast carcinoma: Cardiotoxicity of chemotherapeutic agents: Superior detection of cardiotoxicity during chemotherapy using biomarkers. Epidural anesthesia and cancer recurrence rates after radical prostatectomy. I Guideline of the perioperative evaluation. Outros sinais observados incluem edema de membros inferiores, hepatomegalia, ascite e taquicardia.

G protein-independent G1 cell cycle block and apoptosis with morphine in adenocarcinoma cells: Local anaesthetics do not affect protein kinase C function in intact neuroblastoma cells. Doxorubicin and paclitaxel in the treatment of advanced breast cancer: Physical activity and public health: Protective effect of carvedilol on daunorubicin-induced cardiotoxicity and nephrotoxicity in rats.

Characteristics and outcomes of patients with cancer requiring admission to intensive care units: Curr Treat Options Cardiovasc Med.