Tropical sprue is an acquired chronic diarrheal disorder of unclear etiology affecting residents of and visitors to tropical regions. Patients usually present with . English Spanish online dictionary Term Bank, translate words and terms with different pronunciation options. ESPRUE TROPICAL trastorno de diarrea crónica con mala absorción y deficiencia nutricional etiología desconocida regiones tropicales.

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Infect Dis Clin North Am 12 — Patients usually present with profuse diarrhea, weight loss, and malabsorption, notably of vitamin B12 and folate.

Curr Gastroenterol Rep ; 7: The following investigation results are suggestive:. Crohn’s disease Crohn’s disease is increasingly being diagnosed in tropical countries, 535455 and is an important differential diagnosis for tuberculosis.

Tropical sprue – Wikipedia

Chowkhamba Sanskrit Series Office, Use of nitazoxanide for gastrointestinal tract infections: Clin Sci Mol Med Suppl 55 — Gastroenterology 70 — The clinician needs to consider various factors when evaluating such patients. Asymptomatic Cryptosporidium carriage in rural South Indians. Primary malabsorption Tropical enteropathy The mucosa of the small intestine of residents of the tropics espfue structurally different from that of residents of temperate countries. Malabsorption in Crohn’s disease may occur as a result of several esprje.


Kartalija M, Sande M A. Endoscopically, tropical sprue may resemble coeliac disease, with scalloping of the duodenal mucosa. Chapter 16 Tropical Sprue; Kwashiorkor Sprue, seprue tropical and nontropical, has been a subject of great interest to the medical community ever since it was initially described over years ago. Indian J Gastroenterol 15 — Aetiology The aetiology of tropical sprue remains unknown. In the past two decades, the profile of malabsorption has changed in tropical countries, probably related to changes in hygiene and sanitation.

Tropical sprue in expatriates from the tropics living in the continental United States. Bacterial contamination of the small bowel was described in returning expatriates who developed tropical sprue, 89 as well as in the indigenous population from several regions with endemic tropical sprue.

It may follow as a sequel to epidemics of acute gastroenteritis. Sporadic tropical sprue is still an important cause of malabsorption in adults and in children in South Asia. Bile acid malabsorption occurs as a result of terminal ileal involvement and may contribute to diarrhoea. A milder form of chronic diarrhoea, steatorrhoea and a marked weight loss follows this.

It is important to take biopsy specimens from beyond the second part of the duodenum, as villi in the second part may be shorter than they are more distally in the duodenum and in the jejunum.

Malabsorption of fat, vitamin B 12 and xylose, as well as increased mucosal permeability, has been noted in a large number of healthy residents of the tropics.


Vitamin B 12 and folate deficiency, rarely iron deficiency. Diseases of the digestive system primarily K20—K93— This page was last edited on 15 Novemberat It is of interest despite the fact that it is unknown in many parts of the world and, even where endemic primarily India, Southeast Asia and the Caribbeanit affects relatively few of the population compared with the millions who suffer from parasitic and other tropical diseases.

Nutrient malabsorption in tropical sprue arises from involvement of both the proximal and distal small intestine.

Peroral capsule biopsy of the jejunal mucosa has been replaced by endoscopically obtained duodenal mucosal biopsy. Persistent diarrhea in the returned traveler.

Tropical sprue: revisiting an underrecognized disease.

N Engl J Med — Night blindness, corneal xerosis, Bitot’s spots. Diagnosis of tropical sprue can be complicated because many diseases tgopical similar symptoms. Am J Med 89 — Malabsorption can be treated by an oral dose of a pancreatic enzyme preparation such as Creon with every meal.